FAQ’s

Surgi-ORC^® is a resorbable oxidized cellulose material in a sterile fabric meshwork. When Surgi-ORC^® is applied to the bleeding area, it swells into a brownish/black gelatinous mass that aids in the clotting process.

For additional Info:  https://doi.org/10.1016/j.carbpol.2019.115585

When Surgi- ORC^® haemostat when comes in contact with blood, it forms a brownish or black gelatinous mass. This gelatinous mass acts as a physical matrix to which platelets can adhere. With platelet aggregation and formation of platelet-fibrin plug, meanwhile, the swelling material generates pressure on the surrounding tissue contributing to haemostasis.

Surgi – ORC^® is available in four variants viz. ORIGINAL, KNIT, FIBRIL and NON-WOVEN / SNOW of Surgi-ORC^®

It generally takes 3 to 4 minutes to stop bleeding or achieve Hemostasis with Surgi ORC^®

Surgi-ORC^® is a sterile cellulose based thrombogenic material used to control bleeding originating from delicate and/or friable tissues. It is commercially available as a gauze like material and is generally inert and bio absorbable.

Yes, Surgi-ORC^® Absorbable

Surgi-ORC^® Original, Fibril and Knit absorbable haemostats are composed of oxidized regenerated cellulose and are sterile, absorbable knitted fabrics that are flexible and adhere readily to bleeding surfaces. 

For additional Info: https://doi.org/10.1021/acsbiomaterials.7b00382

Absorption depends on; Haemostat amount used, tissue type and blood saturation degree. Generally, it is completely absorbed within 7-14 days. 

For additional Info: https://doi.org/10.1016/j.carbpol.2012.01.058

Surgi-ORC^® decreases the pH of its surroundings. The dissolution of Surgi-ORC^® depends on the quantity, site of implantation and the environmental factors, and the process may last for between 7-14 days.

For additional Info: https://doi.org/10.1007/s10353-013-0222-z

Yes, Surgi-ORC^® Haemostat can be cut into the desired dimension.

Surgi-ORC^® Haemostats is already available in different dimensions as required in market and as per different surgical conditions. However, as per need surgeon can also further cut them into desired dimensions prior to usage.

Surgi-ORC^® is an adjunctive Haemostats. It can be used assist to control bleeding from capillary, venous and small arteriolar vessels. In emergency/trauma situation Surgi-ORC^® can assist well in Haemostasis & serve as a haemostatic adjunct in the control of local haemorrhage.

For additional Info: https://doi.org/10.1186/s12893-018-0398-z

Surgi – ORC^®, ORIGINAL is  indicated for use in

 Cardiovascular and Thoracic Surgery: Anastomotic sites

General Surgery: Cholecystectomy, Liver and Spleen Laceration, Port Site Bleeding

ENT Surgery: Tonsillectomy

Plastic Surgery: Skin Grafting

Surgi – ORC^®, KNIT is indicated for use in

Cardiovascular and Thoracic Surgery: Cannulation sites, Anastomotic sites in CABG and Valve Repair/ Replacement

General Surgery: Liver Transplant, Resection and Repair, Splenic Injury

Surgi – ORC^®, FIBRIL is indicated for use in

Neurosurgery: Epidural Oozing and Capillary Oozing during Craniotomy, Laminectomy, Surgery on Tumour Bed, Head Trauma, Spine and Spinal Cord Surgeries

Cardiovascular and Thoracic Surgery: Carotid Endarterectomy, Abdominal Aortic Aneurysm, Sternum Closure in CABG and Valve Repair/Replacement 

Orthopaedic Surgery: Femur Shaft Reduction and Fixation

Surgi – ORC^® NON-WOVEN / SNOW is specifically indicated for use in

Gynaecological Surgeries: Laparoscopic hysterectomy

However, the use of the Surgi ORC^® variants in different surgeries is left to the discretion of the Physician.

Surgi-ORC^® can be effective to continuous Bleeding to moderate bleeding conditions.

For additional Info: https://doi.org/10.2147/oaem.s205006

Surgi-ORC^® haemostat should not be used on non-haemorrhagic serious oozing surfaces, since body fluids, except whole blood, such as serum, do not react with Surgi-ORC^® haemostat to give satisfactory results.

No, Antibacterial Activity of Surgi-ORC^® does not depend on any external agent. 

The antibacterial property of Surgi-ORC^® is due to the inbuilt bactericidal characteristic of Oxidized Regenerated Cellulose itself. The pH of Oxidized Cellulose created by oxidation of cellulose, tends to inhibit the growth of microorganisms including some strains of antibiotic resistant organisms.

For additional Info: https://doi.org/10.1089/109629603322419599

Surgi-ORC^® haemostat is bactericidal in vitro against a wide range of gram positive and gram negative organisms including aerobes and anaerobes. The antibacterial property helps in prevention of Surgical Site infection which can occur during the surgery, however, Surgi-ORC^® haemostat is not an alternative to the systemically applied therapeutic or prophylactic antimicrobial agents.

Surgi-ORC^® is not recommended to be used in packing and wadding on surgical sites as it may create difficulty for drainage and exert unwanted pressure.

Surgi-ORC^® must always be removed after haemostasis is achieved, since it will swell and could exert unwanted pressure. The minimum effective amount of oxidized cellulose-based topical haemostatic should be used, and excess material not contributing to haemostasis should be removed, because of the risk of foreign body reactions.

Surgi-ORC^® haemostats should not be moistened with water or saline as it may affect the haemostasis effect. The haemostatic effect of Surgi-ORC^® Absorbable Haemostat is greater when it is applied dry.

Topical hemostats are not intended for primary treatment of coagulation disorders hence included in IFU under warnings. However, topical hemostats like Fibrin related sealants and adhesives can be used as adjuvants for achieving hemostasis in patients with coagulation disorders

For additional Info: https://dx.doi.org/10.1186%2Fs12893-018-0398-z

Surgicel from Ethicon

The sponges consist of PVA (polyvinyl alcohol) material which is capable of absorbing fluid several times of their own weight.

For additional Info: http://www.pvasponge.com/images/Introduction_to_PVA_Sponge.pdf

SURGI-PVA^TM ENT Sponges are intended to be used for placing inside the nasal cavities or ear canal for epistaxis and post-operative surgery, which expands when moistened to assist in management of fluids i.e. fluid control and drainage control and tamponade or haemostasis.

SURGI-PVA^TM Ophthalmic Sponges are intended to be used in ophthalmic or microscopic surgical procedures to assist in absorbing excess fluids from the operative field in management of fluid i.e. fluid control and drainage control.

For Additional Info: https://www.ent-cyprus.com/en/nose/functional-endoscopic-sinus-surgery-fess/

Please refer the Below IFU Link – USER PROCEDURE for method of usage of PVA Sponges.

https://dx.doi.org/10.3791/3885

No, Surgi-PVA^TM is available in different dimensions and shapes required in different surgeries. Further, it need not to be cut in different dimensions.

No. Surgi- PVA^TM is not Absorbable.

For Additional Info: https://www.ejo.eg.net/text.asp?2018/34/4/253/244885

No, Surgi-PVA^TM Sponges is strictly prohibited to contact the PVA sponge with organic solvents.

SURGI-PVA^TM Sponge exhibits no antimicrobial properties, they are not bacteriostatic towards pre-existing infections, nor do they prevent the occurrence of new infections. In the case of pre-existing infections, it is recommended that appropriate treatment should be instituted.

SURGI-PVA^TM Sponge is not suitable to be moistened with an alcoholic solution, as the structure of sponge may change.

After placement of the product more than three days, the evaluation by physician is suggested for further usage.

Yes, Nasal packing is important in critical nasal surgeries, however its left to the discretion of ENT surgeon on usage of nasal packing after FESS

For Additional Info: https://doi.org/10.5005/jp-journals-10013-1320

Merocel from Medtronic

FLOGEL^® matrix provides an environment for platelets to adhere and aggregate within, building on the patient’s natural coagulation cascade.

FLOGEL^® typically stops bleeding within 2 to 5 minutes after application. In some cases, it may take up to 10 minutes without the addition of thrombin. With thrombin, it can work even faster, sometimes within 1.5 minutes.

FLOGEL^® can be used with thrombin but the instruction of use supplied with thrombin should be scrupulously followed before mixing.

FLOGEL^® is indicated for use in surgical procedures (except ophthalmic) where traditional methods of haemostasis are ineffective or impractical. It can be used with or without thrombin to achieve haemostasis.

Yes, FLOGEL^® is safe to use during surgery. It has been designed and tested foreffectiveness in control of bleedingwhen used by experienced surgeons.

FLOGEL^® is mainly used in surgical procedures (except ophthalmic), where traditional methods to control bleeding are not effective or practical. However, it should not be used in certain situations such as closure of skin incisions or in patients with specific allergies. Ref. Instruction for use.

FLOGEL^® can be used by experienced surgeons in various types of surgical procedures (except ophthalmic). The intended patient population includes individuals of all ages and genders requiring haemostasis in surgical procedures. However, the use of FLOGEL has not been established in the patients with known allergies to the gelatin, children and pregnant women. Ref. Instruction for use.

Yes, FLOGEL^® should not be used in patients with known allergies to porcine gelatin or in intravascular compartments. It should also not be used in closure of skin incisions or areas with absence of active blood flow.It should not be injected into the vessels. Ref. Instruction for use.

Yes, FLOGEL^® is absorbed by the body. It is designed to break down and absorbed completely within 4 weeks when used in appropriate amounts.

The safety and effectiveness of FLOGEL^® have not been established in children or pregnant women. It is mainly intended for use in adult patients undergoing surgery.

FLOGEL^® should be disposed of according to medical waste disposal guidelines and local regulations. It should be handled carefully to prevent contamination and potential harm to the environment.

Yes, FLOGEL^® is available in various sizes (5ml, 6ml, 8ml and 10 ml) to accommodate different surgical needs. The size of the product needed depends on the extent of the surgery and the amount of bleeding that needs to be controlled.

Mix FLOGEL^® with sterile sodium chloride (Sterile Saline using empty syringe provided in Kit)) solution. Once the haemostatic matrix is mixed with sterile saline, the appropriate applicator tip should be attached to the syringe for product delivery to the bleeding sites.  In surgical settings, an alternative delivery system or instrument/applicator may also be used as needed, particularly for reaching challenging and remote bleeding surgical sites. Ref. Instruction for use.

FLOGEL^® supplied in various sizes (5ml, 6ml, 8ml and 10 ml)   and is provided in a sterile blister tray with all sterile components and such a tray, packed in an outer Tyvek pouch followed by one secondary carton.

FLOGEL^® is ready to use in 30 seconds once the sterile saline/thrombin is uniformly mixed.

FLOGEL^® is packed in Sterile double barrier packaging and is provided in a sterile blister tray with all sterile components and such a tray, packed in an outer Tyvek pouch followed by one secondary carton.

Surgiflo from Ethicon, Floseal from Baxter

FLOGEL^® has a shelf life of 2 years upon meeting storage conditions. Ref. Labels.

No, we can’t re-sterilize FLOGEL^®. It is for single use only.

FLOGEL^® should be stored at controlled temperature between 2°C-25°C.

HaemoVet^®is made up of highly purified first grade gelatin material.

HaemoVet® is available in various forms including sponges (HaemoVet^® Flex, HaemoVet^® Cubes), powder, and HaemoVet^® Silver Cubes which are impregnated with 5% colloidal silver.

HaemoVet^® is indicated for surgical procedures (except ophthalmic) when control of capillary or small venous or arteriolar bleeding (oozing bleeding) by pressure, ligature or other conventional procedures is ineffective or impractical.

The sponge can be used dry or saturated with sterile saline solution. It should be cut to the desired size, roll between the fingers and lightly compress to fit in the cavity or socket. Following the insertion into the cavity or socket, light finger pressure should be applied for one or two minutes.

HaemoVet® Powder can be applied as a dry powder or saturated with sterile saline solution. When HaemoVet® Powder (1 gm/ 3 gm/ 5 gm) in a container used, add sterile saline solution 3-4 mL/g to prepare a doughy paste, 4-5 mL/g to prepare a paste or 6-7mL/g to prepare a mousse. The resulting doughy, paste or mousse may be smeared or pressed against bleeding surface by hand. When bleeding stops, the excess product should be removed.

When HaemoVet® Powder (1 gm/ 2 gm/ 3 gm/ 5 gm) in Bellow Bottle used as a dry powder. Remove the cap; pump the desired amount of HaemoVet® Powder by holding the neck of bottle by fingers and pressing the mini-vac part of the bottle by thumb. Replace the cap after use. An applicator may be attached to the bellow bottle, if desired. The trimmable applicator tip should be cut at a square angle to avoid creating a sharp tip, if desired. The dry powder may also be dispensed directly from the bellow bottle. Compress the source of bleeding for 2-3 minutes using dry compress afterwards. When bleeding stops, the excess product should be removed.

HaemoVet^® Silver Cubes contain 5% colloidal silver, which offers antimicrobial properties and aids in wound treatment.

The size of the sponge can be adjusted to fit into the wound cavity if needed, sponge can be cut to desired size without squeezing. More than one HaemoVet® Silver Cubes can be used for large wounds. Place the sponge as dry and un-squeezed in the fresh, blood filled wound cavity. Allowed to absorb as much blood as possible.

HaemoVet^® products should be stored in their original packaging in a clean, dry room at a temperature not exceeding 30°C. They should not be refrigerated or frozen and should not be used after the expiry date.

No, HaemoVet^® products are for single use only and should not be re-sterilized or reused.

HaemoVet^® is completely absorbed within <4 weeks.

Yes, HaemoVet^® is sterilized by gamma sterilization.

HaemoVet^® has a shelf life of 5 years upon storage.

Yes, the constituent polymer in HaemoVet^® is considered safe for digestion. However, it is not advised for consumption.

VETIGEL^® from Cresilon, Vetspon^® from Ferrosan medical devices, ClotIt Vet Hemostatic Powder from Protégé Biomedical, HEMABLOCK^® by Vet Brands International