Beyond Bleeding Control: The Scientific Advancements of Oxidized Regenerated Cellulose in CABG

Cardiovascular disease remains one of the leading causes of death worldwide. Among the many treatment options available, Coronary Artery Bypass Grafting (CABG) is a life-saving procedure that has been helping patients regain their health and vitality for decades. Postoperative bleeding is still one of the most serious complications of open heart surgery.

Following CABG, the reexploration rate for hemorrhage was reported to be between 2% and 6%. Patients who are at high risk for sternal instability and wound-healing issues following cardiac surgery require an outstanding material known as oxidised regenerated cellulose (ORC) that enhances sternal bleeding control and reduces infection rates. One study found that ORC hemostats in knit form reduced sternal bleeding more effectively than conventional ORC. 

ORC Knit has triple density, 150% thickness, and is more tearproof than the classic ORC patch. The enlarged surface matrix provided an additive hemostatic effect as a result of improved platelet adhesion. Furthermore, ORC combined with electrocauterization can be used safely to treat sternal intramedullary space hemorrhage.

Source:
https://doi.org/10.3906/sag-1207-9
10.1016/j.jtcvs.2005.04.013